Only the killed (Salk) vaccine can safely be used in children with symptomatic HIV infection. However, the live vaccine is safe in infants who are HIV infected but well.
Polio vaccine can be given to children with diarrhoea and vomiting but an extra dose should later be given as the diarrhoea or vomiting may prevent successful immunisation.
Very rarely (1 in 500 000), paralysis can follow use of oral Sabin polio vaccine. This does not occur with the killed Salk vaccine. All cases of acute flaccid paralysis must be notified to determine whether polio has been eradicated.