Stage 3 HIV infection is recognised by:

• Moderate unexplained weight loss or failure to thrive. These children are usually chronically unwell with a poor appetite. Their weight is 60 to 80% of that expected for their age.
• Unexplained fever
• Unexplained persistent diarrhoea for more than 14 days
• Oral candidiasis (thrush) after the newborn period. The candidiasis is often severe, recurrent and responds poorly to topical treatment.
• Pulmonary tuberculosis
• Severe recurrent presumed bacterial pneumonia
• Herpes zoster or severe herpes simplex infection
• Symptomatic lymphoid interstitial pneumonia (LIP)
• Unexplained anaemia, neutropaenia (low white blood cell count) or thrombocytopaenia (low platelet count)
• Gingivitis (gum infections and bleeding)