Insect control is most important. Treat the rash with calamine lotion which decreases the itching. An oral antihistamine syrup, such as chlorpheniramine (Chortrimetron), promethazine (Phenegan) or hydroxyzine (Aterax), also decreases itching and helps the child to sleep. Do not use antihistamine cream. In severe cases, use 1% hydrocortisone cream for a few days as for eczema. Treat any secondary impetigo.
Non sedating antihistamines such as cetirizine (Zyrtec) and loratidine (Clarityne) are effective but expensive.